CASE STUDY | ADVERTISING
When Rare Disease Diagnosis Was Missed, We Drove Recognition and Action.
THE CHALLENGE
Addressing Gaps in Recognition and Awareness in a Rare, Under-Recognized Disease
A pharmaceutical company sought to improve diagnosis and treatment uptake for a therapy indicated for a rare, chronic, and progressive disease.
The condition was often underdiagnosed or misdiagnosed due to nonspecific symptoms and limited awareness. Existing treatment approaches focused primarily on symptom management and were not specific to the underlying disease.
As a result, both HCP and patient awareness remained limited, creating a need for education that could strengthen recognition of the condition and introduce a new treatment option.
THE BREAKTHROUGH
Reframing HCP Education to Address Unmet Need and Enable Action
BGBx identified that increasing diagnosis and treatment uptake required more than traditional promotion.
Through the Breakthrough Process, powered by 3D Science, the team developed an approach that combined HCP education, patient storytelling, and broader awareness-building to highlight unmet need and the impact of the disease.
The Solution
- Differentiation and patient-led positioning using real patient experiences
- Patient empowerment campaigns to support better physician conversations
- Full-spectrum omnichannel education and promotion across HCP and patient audiences
- Advocacy and KOL engagement through live broadcasts and stakeholder engagement
- Congress and scientific activation using patient cases and real-world experiences
- Peer-to-peer and speaker programs to reinforce education and engagement
THE RESULTS
Increased Awareness, Engagement, and Early Treatment Uptake in a Rare Disease Market
The integrated campaign drove significant awareness and engagement across both HCP and patient audiences. Fifty percent of site visitors were inspired to talk to their doctor, contributing to 2,600 patients initiating treatment within the first six months of FDA approval.
~5M
Targeted TV Impressions
Rare disease awareness campaign
40.5M
Web Impressions
Expanded digital reach
1.8M
Social Impressions
Patient and HCP engagement
Let’s Build Your Next Rare Disease Breakthrough
At BGBx, we design integrated campaigns that connect education, engagement, and activation, helping brands strengthen awareness, identification, and treatment uptake in rare disease markets. Let’s build your next breakthrough together.

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